EHA 2024 | Real-world dose de-escalation of teclistamab in patients with R/R myeloma
Saad Usmani, MD, MBA, FACP, Memorial Sloan Kettering Cancer Center, New York, NY, discusses real-world dose de-escalation of teclistamab in patients with relapsed/refractory (R/R) multiple myeloma (MM). While the MajesTEC-1 trial (NCT04557098) demonstrated the efficacy of teclistamab, it also highlighted a high risk of infection. Patients at Dr Usmani’s center who underwent dose de-escalation after 3 treatment cycles maintained a sustained response at 6 months, indicating this was an effective strategy to mitigate infection risk. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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