EHA 2024 | Preliminary results from a Phase Ib trial of AS-1763, a novel non-covalent BTKi, in CLL/MCL
Nitin Jain, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, shares the preliminary results from the ongoing Phase Ib trial (NCT05602363) of AS-1763, a novel non-covalent BTK inhibitor (BTKi), in patients with previously treated B-cell malignancies, primarily R/R chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). The trial is still in the dose escalation phase, but so far, the agent appears to be safe, with no treatment-related adverse events reported, and has led to partial remissions in patients with CLL. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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